{"id":1503,"date":"2023-12-22T20:11:15","date_gmt":"2023-12-22T20:11:15","guid":{"rendered":"https:\/\/www.bidrx.com\/blog\/?p=1503"},"modified":"2023-12-22T21:28:31","modified_gmt":"2023-12-22T21:28:31","slug":"guide-to-snris","status":"publish","type":"post","link":"https:\/\/www.bidrx.com\/blog\/depression-medications\/guide-to-snris\/","title":{"rendered":"Reference Guide to Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)"},"content":{"rendered":"<p><b>Highlights\u00a0<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Serotonin and norepinephrine reuptake inhibitors (SNRIs) are used to treat various mental health disorders, including depression, major depressive disorder, and generalized anxiety disorder.<\/span><\/li>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">SNRIs are unique in that they target two types of neurotransmitters: serotonin and norepinephrine.<\/span><\/li>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">SNRIs and other antidepressants may increase suicidal thoughts and behaviors, especially in adolescents and young adults.<\/span><\/li>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">SNRIs are generally safe but may not be right for everyone.<\/span><\/li>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">This guide to SNRIs explores potential interactions with other medications, such as MAOIs, amphetamines, blood thinners, and antiarrhythmics.<\/span><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"font-weight: 400;\">Many people experience sadness or irritability. But when these feelings don\u2019t dissipate over time or interfere with your daily life, there might be more going on beneath the surface. <\/span><a href=\"https:\/\/www.bidrx.com\/blog\/depression-medications\/depression-causes-symptoms-diagnosis-treatment\/\"><span style=\"font-weight: 400;\">Depression<\/span><\/a><span style=\"font-weight: 400;\"> is a reality for <\/span><a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/depression\"><span style=\"font-weight: 400;\">more than 280 million people<\/span><\/a><span style=\"font-weight: 400;\"> worldwide, and medications like serotonin and norepinephrine reuptake inhibitors (SNRIs) provide relief.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When depressive symptoms don\u2019t go away on their own, prescription medications can help individuals live a normal life. These medications work by balancing chemicals in the brain that contribute to feelings of happiness and mood regulation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Learn more in this guide to SNRIs and what to expect if your doctor prescribes an SNRI to treat your depression.\u00a0<\/span><\/p>\n<h2>What Are SNRIs?<\/h2>\n<p><span style=\"font-weight: 400;\">SNRIs are a type of antidepressant that treat various mental health disorders. They are a common prescription in the United States.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples of conditions SNRIs can treat include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Major depressive disorder (MDD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Generalized anxiety disorder (GAD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Social anxiety disorder<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Panic disorder<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some chronic pain conditions, such as nerve pain<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Off-label uses for SNRIs may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hot flashes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Night sweats<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary incontinence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Peripheral neuropathy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Attention deficit\/hyperactivity disorder (ADHD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Migraines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Obsessive-compulsive disorder (OCD)<\/span><\/li>\n<\/ul>\n<h2>How Do SNRIs Work?<\/h2>\n<p><span style=\"font-weight: 400;\">SNRIs work by affecting the neurotransmitters in the brain, specifically serotonin and norepinephrine. Neurotransmitters are chemical messengers that aid communication between nerve cells. These two neurotransmitters play a role in regulating mood, emotions, and perceptions of pain, which is why they\u2019re commonly used to treat depression.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The neurotransmitters deliver messages in the brain. When the \u201cmission\u201d is complete, they are reabsorbed by the nerve cells that released them \u2014 a process called <\/span><b>reuptake<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s theorized that <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2950973\/#\"><span style=\"font-weight: 400;\">depression occurs<\/span><\/a><span style=\"font-weight: 400;\"> when neurotransmitters like serotonin, norepinephrine, or dopamine are depleted in the brain. There\u2019s simply not enough to keep you feeling happy.\u00a0\u00a0<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1506\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/potential-candidate-for-serotonin.jpg\" alt=\"potential candidate for serotonin\" width=\"780\" height=\"521\" \/><\/p>\n<p><span style=\"font-weight: 400;\">By inhibiting the reuptake process, more neurotransmitters are available in the brain, helping to stabilize moods and positive feelings.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">SNRIs inhibit the reuptake of serotonin and norepinephrine. This increases the amount of each neurotransmitter in the brain, which improves communication between nerve cells. By better balancing these chemicals, antidepressants have a positive impact on emotions and well-being.<\/span><\/p>\n<h2>Description and Examples of SNRIs<\/h2>\n<p><span style=\"font-weight: 400;\">SNRIs are one of several subtypes of antidepressants, which also include <\/span><a href=\"https:\/\/www.bidrx.com\/blog\/depression-medications\/guide-to-ssris\/\"><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> (SSRIs) and tricyclic antidepressants (TCAs).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples of SNRIs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/venlafaxine-hcl-100-mg-tablet\"><span style=\"font-weight: 400;\">Venlafaxine<\/span><\/a><span style=\"font-weight: 400;\"> (Effexor)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/desvenlafaxine-succnt-er-100mg\"><span style=\"font-weight: 400;\">Desvenlafaxine<\/span><\/a><span style=\"font-weight: 400;\"> (Pristiq)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/duloxetine-hcl-dr-20-mg-cap\"><span style=\"font-weight: 400;\">Duloxetine<\/span><\/a><span style=\"font-weight: 400;\"> (Cymbalta)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Levomilnacipran (Fetzima)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">SNRIs are unique because of the neurotransmitters they target. Unlike SSRIs, which focus on serotonin, SNRIs also target norepinephrine. TCAs affect serotonin, norepinephrine, and other neurotransmitters as well.\u00a0<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1507\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/woman-taking-SNRIs.jpg\" alt=\"woman taking SNRIs\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Treatment and use cases can also vary. While SSRIs are mainly used to treat depression, SNRIs can treat depression and anxiety disorders. TCAs have a still broader range of uses.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ultimately, the choice of antidepressants depends on several factors, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The patient\u2019s specific condition(s)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medical history<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Potential side effects<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Response to previous treatments<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Your doctor will conduct a thorough evaluation of your health history and symptoms prior to recommending an antidepressant.<\/span><\/p>\n<h3>Warnings and Contraindications \u2014 SNRIs<\/h3>\n<p><span style=\"font-weight: 400;\">While generally safe and effective, SNRIs come with warnings and contraindications that should be considered before taking these medications. Warnings and contraindications may vary by prescription.\u00a0<\/span><\/p>\n<h4>Warnings<\/h4>\n<p><span style=\"font-weight: 400;\">Common warnings with SNRIs include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Suicidal thoughts<\/b><span style=\"font-weight: 400;\">. SNRIs are known to increase the risk of suicidal thoughts and behaviors, especially in adolescents and young adults. Report any suicidal feelings or behaviors to your doctor immediately.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Serotonin syndrome<\/b><span style=\"font-weight: 400;\">. SNRIs increase serotonin levels in the brain, which could lead to the development of serotonin syndrome, a rare but serious condition. Symptoms include:<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Sweating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Stiff muscles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Antidepressant discontinuation syndrome<\/b><span style=\"font-weight: 400;\">. Missing doses or abruptly discontinuing your medication may create unwanted side effects, such as dizziness, nausea, or insomnia. Never stop an antidepressant on your own; these medications require a gradual taper done under a doctor\u2019s supervision.<\/span><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1508\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/woman-experiencing-a-headache.jpg\" alt=\"woman experiencing a headache\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Additional warnings may exist for individual SNRI medications. For example, <\/span><a href=\"https:\/\/www.aao.org\/eye-health\/symptoms\/dilated-pupil\"><span style=\"font-weight: 400;\">mydriasis<\/span><\/a><span style=\"font-weight: 400;\"> has occurred in patients with narrow-angle glaucoma who were taking desvenlafaxine. This medication features additional warnings for patients with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypomania<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Renal impairment<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hyponatremia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Interstitial lung disease<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Speak with your doctor to learn more about the risks and benefits of your specific medication.<\/span><\/p>\n<h4>Contraindications<\/h4>\n<p><span style=\"font-weight: 400;\">SNRIs are typically contraindicated in patients:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Who have a known hypersensitivity to the drug<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are taking an MAOI<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Have stopped taking an MAOI within the previous 14 days<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This information is not a substitute for professional medical advice. Always consult with your doctor prior to taking any medication, including SNRIs. They can discuss the individual risks and benefits of a specific SNRI and provide guidance on its safe and effective use based on your personal medical history.<\/span><\/p>\n<h3>Side Effects \u2014 SNRIs<\/h3>\n<p><span style=\"font-weight: 400;\">Side effects may vary between individuals and medications. Some of the most common side effects of SNRIs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased libido<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heartburn<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nervousness<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Rare but serious side effects should be reported to your doctor. These include but are not limited to:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hallucinations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain<\/span><\/li>\n<\/ul>\n<h3>Drug Interactions \u2014 SNRIs<\/h3>\n<p><span style=\"font-weight: 400;\">SNRIs may interact with other medications, and some medications should never be taken together. Interactions can vary by prescription, so be sure all your providers know every medication and over-the-counter supplement you\u2019re currently taking to avoid potential interactions.\u00a0<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1509\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/pills-and-pill-bottles.jpg\" alt=\"pills and pill bottles\" width=\"780\" height=\"437\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Typically, SNRIs should not be taken with the following types of medications:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Amphetamines<\/b><span style=\"font-weight: 400;\">. SNRIs may increase the effects of amphetamines, including jitteriness, nervousness, and anxiety, and may lead to serotonin syndrome.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>MAOIs<\/b><span style=\"font-weight: 400;\">. Taking these two types of drugs may lead to serotonin syndrome.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>TCAs<\/b><span style=\"font-weight: 400;\">.Using SNRIs with tricyclic antidepressants (TCAs) may increase the risk of heart problems and serotonin syndrome.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Blood thinners<\/b><span style=\"font-weight: 400;\">. Warfarin and <\/span><a href=\"https:\/\/www.bidrx.com\/blog\/headache-medications\/guide-to-nsaids\/\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\"> may increase the risk of bleeding.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Antiarrhythmic drugs<\/b><span style=\"font-weight: 400;\">. This combination may increase the risk of an irregular heartbeat that can be serious and potentially life-threatening.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">For a complete list of potential interactions, check your medication using the <\/span><a href=\"https:\/\/www.drugs.com\/drug_interactions.html\"><span style=\"font-weight: 400;\">Drug Interaction Checker<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2>Are SNRIs the Right Option for Your Depression?<\/h2>\n<p><span style=\"font-weight: 400;\">SNRIs have been shown to be highly effective in treating certain depressive disorders. They target two unique neurotransmitters, serotonin and norepinephrine, to increase their availability in the brain. For many patients, SNRIs allow them to lead happy and productive lives.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, no medication is without risk. It\u2019s important to review the potential side effects, warnings, and contraindications prior to taking any medication. Let your doctor know all of the prescriptions, over-the-counter medications, and supplements you\u2019re taking to avoid potential adverse effects.<\/span><\/p>\n<h2>Get the Lowest Price for Your SNRIs<\/h2>\n<p><span style=\"font-weight: 400;\">If you\u2019re looking to save money on SNRIs or other medications, BidRx can help. Create a free account, share your prescription, and let pharmacies compete for your business. You can select the offer that best matches your budget and have your prescriptions delivered to your door.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Find your SNRI on our <\/span><a href=\"https:\/\/www.bidrx.com\/home\/Contents\/medication\"><span style=\"font-weight: 400;\">erectile dysfunction<\/span><b> medication page<\/b><\/a> <span style=\"font-weight: 400;\">and place your bid today.<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">This information is intended for general informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication.\u00a0<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Read this guide to SNRIs to learn more about how this drug class treats depression, potential side effects, drug interactions, contraindications, and more.<\/p>\n","protected":false},"author":7,"featured_media":1504,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-1503","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-depression-medications"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1503","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/comments?post=1503"}],"version-history":[{"count":2,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1503\/revisions"}],"predecessor-version":[{"id":1510,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1503\/revisions\/1510"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media\/1504"}],"wp:attachment":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media?parent=1503"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/categories?post=1503"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/tags?post=1503"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}