{"id":1474,"date":"2023-12-11T10:42:22","date_gmt":"2023-12-11T10:42:22","guid":{"rendered":"https:\/\/www.bidrx.com\/blog\/?p=1474"},"modified":"2023-12-10T20:54:24","modified_gmt":"2023-12-10T20:54:24","slug":"about-prednisolone","status":"publish","type":"post","link":"https:\/\/www.bidrx.com\/blog\/allergy-medications\/about-prednisolone\/","title":{"rendered":"About Prednisolone: A Patient&#8217;s Guide"},"content":{"rendered":"<p><b>Highlights\u00a0<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><b>Prednisolone, an active form of prednisone, is a synthetic glucocorticosteroid with anti-inflammatory and immunosuppressive properties. It works by mimicking cortisol, reducing inflammation, and suppressing immune responses, making it useful in treating a variety of conditions.<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Prednisolone is prescribed for a range of diseases, including hormonal disorders, inflammatory conditions like arthritis and lupus, allergic disorders, and certain types of cancer.\u00a0<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Unlike prednisone, which requires liver conversion, prednisolone is directly usable by the body and has a higher bioavailability.\u00a0<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>While effective, prednisolone can cause numerous side effects ranging from mild to severe. It also has numerous potential drug interactions, highlighting the importance of discussing all medications and supplements with healthcare providers.<\/b><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"font-weight: 400;\">Prednisolone is a corticosteroid that limits the release of biochemical compounds that cause inflammation. In addition to reducing inflammation, it also helps rein in autoimmune responses. By mimicking the action of the hormone cortisol, prednisolone weakens the immune system, making those who take it more vulnerable to <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/021959s004lbl.pdf\"><span style=\"font-weight: 400;\">infections<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2>What Is Prednisolone and What Is It Used For?<\/h2>\n<p><span style=\"font-weight: 400;\">As a potent synthetic corticosteroid, <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-10-mg-tablet\"><span style=\"font-weight: 400;\">prednisolone<\/span><\/a><span style=\"font-weight: 400;\"> suppresses inflammation and the immune system, fights allergies, and exhibits anti-shock action. It is the active form of prednisone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It is a synthetic hormone that acts like cortisol, a natural hormone the adrenal gland secretes. It also reduces sodium secretion from the body, increases potassium retention, and raises glucose levels in the blood.\u00a0<\/span><\/p>\n<h3>The History of Prednisolone<\/h3>\n<p><span style=\"font-weight: 400;\">Prednisolone&#8217;s journey through discovery and development closely paralleled the advancements in the field of corticosteroids.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the 1930s, scientists achieved a breakthrough by isolating the first corticosteroid. Building upon this discovery, the 1940s marked the introduction of the initial synthetic corticosteroids. Notably, in 1950, the pioneers behind the identification of adrenal gland hormones were honored with a Nobel Prize for their groundbreaking contributions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Among these synthetic corticosteroids, prednisone emerged as the foremost discovery. Prednisone operates as a prodrug of prednisolone, meaning it\u2019s inactive on its own; the liver metabolizes it into prednisolone, its active state.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because of its potent anti-inflammatory and immunosuppressive properties, prednisolone began making its mark in the medical field in the late 1950s. Since then, pharmacists have fine-tuned various formulations of the drug, making it an important treatment for conditions such as inflammation, autoimmune disorders, allergies, and more.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The Food and Drug Administration (FDA) approved prednisolone <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/021959s004lbl.pdf\"><span style=\"font-weight: 400;\">in 1955<\/span><\/a><span style=\"font-weight: 400;\">. Today, researchers still study prednisolone and continue to find new applications for the drug.\u00a0<\/span><\/p>\n<h3>Prednisolone\u2019s Uses<\/h3>\n<p><span style=\"font-weight: 400;\">Its multi-pronged action makes prednisolone suitable for the treatment of a wide range of conditions, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hormonal disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Inflammatory conditions like psoriasis, lupus, arthritis, and ulcerative colitis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergic disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dermatologic problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal diseases<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lung diseases<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eye problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Problems of the nervous system<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some infectious diseases<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some nervous system conditions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some types of cancer\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Doctors may also prescribe prednisolone for many off-label uses, like severe allergic reactions, chronic cough, and some blood disorders.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone is a generic drug available under many brand names, including:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Orapred ODT<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Omnipred<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Millipred<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prelone<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pred Forte<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pred Mild<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Veripred<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cotolone<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hydeltrasol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Predicort\u00a0<\/span><\/li>\n<\/ul>\n<h3>Prednisolone vs. Prednisone<\/h3>\n<p><span style=\"font-weight: 400;\">Prednisone is a prodrug that the liver turns into prednisolone. Yet, the two compounds differ in many ways.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Their chemical structures are different. Unlike prednisone, the body can use prednisolone directly, without conversion by the liver.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone has a higher bioavailability than prednisone and may, therefore, be more \u201cpotent.\u201d<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">Read Prednisone vs. Prednisolone: What\u2019s the Difference? to learn more about the differences between the two medications.\u00a0<\/span><\/i><\/p>\n<h2>How Does Prednisolone Work?<\/h2>\n<p><span style=\"font-weight: 400;\">As a glucocorticosteroid, prednisolone works by blocking the activity of some immune cells like white blood cells and macrophages. Immune cells play significant roles in inflammatory responses. The suppression of the immune system happens by the same mechanism.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to immune cells, prednisolone also inhibits cytokines. Cytokines are microscopic proteins that message immune cells and control their growth and activity.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to its anti-inflammatory and immunosuppressive effects, prednisolone can also fight edema (swelling). It decreases the permeability of the blood vessel walls, making it more difficult for fluids to accumulate in tissues.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone also stabilizes cell walls by making them less permeable.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Unfortunately, because of its interference with inflammatory and immune reactions on such deep levels, prednisolone can cause some undesirable <\/span><a href=\"https:\/\/docs.google.com\/document\/d\/178-A99KjmErbChO_dWeXnExj7m38BR-oHrC2otLe7ss\/edit#heading=h.amfevz1fpdgs\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2>What Formulas Are Available for Prednisolone?<\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1476\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/bottle-of-prednisolone.jpg\" alt=\"bottle of prednisolone\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone is available in a wide range of formulas to treat diverse conditions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In oral tablet form, it comes in <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-1-mg-tablet\"><span style=\"font-weight: 400;\">1 milligram<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-2.5-mg-tablet\"><span style=\"font-weight: 400;\">2.5 <\/span><\/a><span style=\"font-weight: 400;\">milligram, <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-5-mg-dosepak-tb\"><span style=\"font-weight: 400;\">5 milligram<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-10-mg-tablet\"><span style=\"font-weight: 400;\">10 milligram<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-20-mg-tablet\"><span style=\"font-weight: 400;\">20 milligram<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-50-mg-tablet\"><span style=\"font-weight: 400;\">50 milligram<\/span><\/a><span style=\"font-weight: 400;\"> doses.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone is also available in <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisolone-15-mg-5-ml-syrup\"><span style=\"font-weight: 400;\">15 milligram\/5 milliliters<\/span><\/a><span style=\"font-weight: 400;\"> syrup and <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisolone-ac-1-eye-drop\"><span style=\"font-weight: 400;\">1% eye drop<\/span><\/a><span style=\"font-weight: 400;\"> forms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other prednisolone formulas are:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oral suspension<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oral liquid<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oral disintegrating tablets<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Injectable solution<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Compounding powder<\/span><\/li>\n<\/ul>\n<h2>Prednisolone Dosage and Administration<\/h2>\n<p><span style=\"font-weight: 400;\">Because of the wide variety of conditions that may be treated with prednisolone, there are no standard dosage guidelines. Doctors determine dosage based on the condition being treated, the patient\u2019s age and medical history, and other factors.\u00a0<\/span><\/p>\n<h2>How Should I Take Prednisolone?<\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1477\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/person-taking-a-couple-of-pills.jpg\" alt=\"person taking a couple of prednisolone pills\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Guidelines vary, based on the form of prednisolone you\u2019re taking. Below are general guidelines:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Always take this drug exactly as your doctor prescribes it. <\/b><span style=\"font-weight: 400;\">Depending on your response to the treatment, your doctor may tweak your dosage. Always take care to update your routine and take only the prescribed doses. Be aware that in some cases, the treatment regimen is every other day.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Follow the instructions on your medicine label.<\/b><span style=\"font-weight: 400;\"> If your oral suspension requires you to shake up the liquid before you measure a dose, do so.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Take special care with disintegrating tablets. <\/b><span style=\"font-weight: 400;\">Don\u2019t remove them from the blister pack until you\u2019re ready to take them. Peel back the foil gently instead of pushing the tablet through it.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Don\u2019t chew disintegrating tablets. <\/b><span style=\"font-weight: 400;\">Allow them to dissolve in your mouth and swallow several times before you eat or drink anything else.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Measure carefully. <\/b><span style=\"font-weight: 400;\">Always use a special dose-measuring syringe, cup, or spoon for measuring doses of liquid prednisolone medication.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Don\u2019t stop taking prednisolone suddenly.<\/b><span style=\"font-weight: 400;\"> You must taper the dose. Only your doctors can tell you how to do that and when to discontinue taking the drug.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Consider wearing a medical tag. <\/b><span style=\"font-weight: 400;\">Prednisolone has a profound effect on the body, influencing its hormonal functions. It can also interact with other medications. If you\u2019re taking prednisolone, it\u2019s wise to wear a medical tag identifying you as a patient under prednisolone treatment.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Follow surgical precautions. <\/b><span style=\"font-weight: 400;\">If you need surgery, you may have to stop taking prednisolone for a while. Ask your doctor for instructions on how to stop and restart your treatment.\u00a0<\/span><\/li>\n<\/ul>\n<h2>What Are the Potential Side Effects of Prednisolone?<\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1479\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/stethoscope.jpg\" alt=\"stethoscope\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone can have many side effects, some of them potentially life-threatening, and it can trigger allergic reactions.\u00a0\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you have an allergic reaction, you need emergency medical help. Some symptoms of an allergic reaction are:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swollen face, throat, or mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itchy and irritated eyes<\/span><i><span style=\"font-weight: 400;\">\u00a0<\/span><\/i><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Left unaddressed, allergic reactions can be fatal.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prednisolone can have other severe side effect, including:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cushing\u2019s syndrome<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling in various body parts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Exhaustion and shortness of breath, even with mild physical efforts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficult or rattling breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Significantly less urination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irregular heartbeats, palpitations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual pain in the arms, neck, or back<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tarry, bloody stools<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe upper-stomach pain and vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Personality changes, mood swings, and unusual thoughts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomit that looks like ground coffee<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Signs of low potassium levels, including unusual thirst and abundant urination, cramping legs, fluttering in the chest, tingling or numbness in the extremities, constipation\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Seek medical help if you experience even one of these symptoms. Some of the more common side effects that may warrant medical attention are:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irritability<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aggression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Having trouble walking, speaking, and thinking<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rashes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal cramping<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow healing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chills and fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain in the eyes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fruity breath odor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of libido<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Menstrual problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Height decrease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Deteriorating vision\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Some of the most common side effects of the drug may not require immediate medical attention unless they take a turn for the worse.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thinning scalp hair<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry scalp<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the stomach<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual fat deposits on the face or neck<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Purple or reddish lines on various body parts\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Side-effect lists are never complete. Drugs like prednisolone may cause other side effects, depending on how each person reacts to it. Do not hesitate to contact your doctor if you are worried about the side effects you experience.\u00a0<\/span><\/p>\n<h2>What Should I Avoid When Taking Prednisolone?<\/h2>\n<p><span style=\"font-weight: 400;\">Prednisolone affects how your immune system works. It reduces the ability of your body to fight infections. When you\u2019re on prednisolone, try to avoid sick people and situations where you may contract an infection. If you come in contact with people with chickenpox or measles infections, talk to your doctor and seek preventive treatment.\u00a0<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1480\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/microscopic-representation-of-an-infection.jpg\" alt=\"microscopic representation of an infection\" width=\"780\" height=\"468\" \/><i><span style=\"font-weight: 400;\">Avoid infected people.<\/span><\/i><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Do not get live vaccines \u2014 those that contain weakened or inactive versions of viruses or bacteria. Live vaccines include influenza, shingles, chickenpox, rotavirus, rubella, and mumps vaccines, among others.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you get a live vaccine while on prednisolone, it will likely not be as effective as it should be. Live vaccines use weakened versions of the germs and viruses against which they provide protection.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Avoid <\/span><a href=\"https:\/\/www.cdc.gov\/vaccines\/vpd\/smallpox\/hcp\/vacc-contraindications.html\"><span style=\"font-weight: 400;\">smallpox vaccines<\/span><\/a><span style=\"font-weight: 400;\">. You can develop severe complications if you get a smallpox vaccine while under treatment with prednisolone.\u00a0<\/span><\/p>\n<h2>What Should I Do If I Miss a Dose of Prednisolone?<\/h2>\n<p><span style=\"font-weight: 400;\">Never double-dose prednisolone. If you forget to take a dose, take it as soon as you remember it unless it is almost time for your next dose. In that case, skip it.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s not a bad idea to call your doctor if you miss a dose. Your particular situation may require a different approach.\u00a0\u00a0<\/span><\/p>\n<h2>What Should I Do If I Overdose on Prednisolone?<\/h2>\n<p><span style=\"font-weight: 400;\">Overdosing on prednisolone should not result in life-threatening symptoms and side effects. If you happen to overdose, however, call the Poison Help line at 1-800-222-1222.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Symptoms of overdose may include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Erectile dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of interest in sex<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood swings<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thinning skin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Easy bruising<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Altered body fat distribution<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acne<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Growth of facial hair in women<\/span><\/li>\n<\/ul>\n<h2>Warnings and Precautions<\/h2>\n<p><span style=\"font-weight: 400;\">Some people can\u2019t take this drug at all. For others, doctors must weigh its likely benefits against the potential side effects and harm it may cause.<\/span><\/p>\n<h3>Who Should Not Take Prednisolone?<\/h3>\n<p><span style=\"font-weight: 400;\">Don\u2019t take prednisolone if you\u2019re allergic to it. Your doctor will probably not prescribe this drug for you if you have a systemic fungal infection. (This does not apply to a local infection, such as athlete\u2019s foot.)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Always talk to your doctor about all medications, supplements, and vitamins you take.\u00a0<\/span><\/p>\n<h3>Who Should Take Prednisolone With Caution?<\/h3>\n<p><span style=\"font-weight: 400;\">Your doctor may not recommend prednisolone if you have an eye infection or have had trouble with a reoccurring form of your condition.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Also, tell your doctor if you suffer from any of the following conditions:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cataracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cushing\u2019s syndrome<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uncontrolled high blood pressure\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tuberculosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thyroid or kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart disease\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">We don\u2019t know whether prednisolone can harm an unborn or nursing baby, so it\u2019s best to exercise caution if you\u2019re pregnant or breast-feeding.\u00a0<\/span><\/p>\n<h2>Are There Any Other Potential Drug Interactions With Prednisolone?<\/h2>\n<p><span style=\"font-weight: 400;\">According to drugs.com, a total of <\/span><a href=\"https:\/\/www.drugs.com\/drug-interactions\/prednisolone-index.html\"><span style=\"font-weight: 400;\">578 drugs<\/span><\/a><span style=\"font-weight: 400;\"> can interact with prednisolone.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Of these, <\/span><a href=\"https:\/\/www.drugs.com\/drug-interactions\/prednisolone-index.html?filter=3\"><span style=\"font-weight: 400;\">71 are major<\/span><\/a><span style=\"font-weight: 400;\"> interactions, <\/span><a href=\"https:\/\/www.drugs.com\/drug-interactions\/prednisolone-index.html?filter=2\"><span style=\"font-weight: 400;\">466 are moderate<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.drugs.com\/drug-interactions\/prednisolone-index.html?filter=1\"><span style=\"font-weight: 400;\">41 are minor<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For the complete interactions list, check the Drugs.com <\/span><a href=\"https:\/\/www.drugs.com\/drug-interactions\/prednisolone.html\"><span style=\"font-weight: 400;\">Prednisolone Interactions Checker<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">No list of potential drug interactions is complete, so let your healthcare provider know if you experience any new or unusual symptoms after taking this medication.<\/span><\/p>\n<h2>Conclusion\/Transition Section<\/h2>\n<p><span style=\"font-weight: 400;\">Prednisolone is a powerful medication used to treat many diseases and conditions. It\u2019s important to understand how it works, the side effects it may cause, and how it interacts with drugs, foods, and other health conditions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Now that you have educated yourself about prednisolone, it\u2019s time to find out how to get it at the lowest price.\u00a0<\/span><\/p>\n<h2>Get the Lowest Price for Prednisolone With BidRx<\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1481\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/12\/young-lady-buying-prednisolone-at-the-pharmacy.jpg\" alt=\"young lady buying prednisolone at the pharmacy\" width=\"780\" height=\"439\" \/><\/p>\n<p><span style=\"font-weight: 400;\">BidRx allows you to create bids for the medications you need. When you create your bid for prednisolone, pharmacies compete to fill your prescription by giving you their <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/prednisone-1-mg-tablet\"><span style=\"font-weight: 400;\">lowest price for prednisolone<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You choose your offer, then have your prescription delivered to your home or, depending on the offer you choose, pick it up at a local pharmacy.\u00a0<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">Please note that this information is intended for general informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication.<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prednisolone is the active form of prednisone. Learn how this corticosteroid works, the conditions it treats, and how to take it for best results.<\/p>\n","protected":false},"author":2,"featured_media":1475,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,16],"tags":[],"class_list":["post-1474","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allergy-medications","category-arthritis-medications"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/comments?post=1474"}],"version-history":[{"count":1,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1474\/revisions"}],"predecessor-version":[{"id":1482,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1474\/revisions\/1482"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media\/1475"}],"wp:attachment":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media?parent=1474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/categories?post=1474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/tags?post=1474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}