{"id":1341,"date":"2023-12-22T16:01:49","date_gmt":"2023-12-22T16:01:49","guid":{"rendered":"https:\/\/www.bidrx.com\/blog\/?p=1341"},"modified":"2023-12-22T20:31:15","modified_gmt":"2023-12-22T20:31:15","slug":"reference-guide-to-beta-blockers","status":"publish","type":"post","link":"https:\/\/www.bidrx.com\/blog\/blood-pressure-medications\/reference-guide-to-beta-blockers\/","title":{"rendered":"Reference Guide to Beta Blockers"},"content":{"rendered":"<p><b>Highlights<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><b>Beta blockers are used to treat heart conditions ranging from high blood pressure to heart failure.<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>This class of drugs blocks beta receptors. This can lower the effects of fight-or-flight hormones, help decrease heart rate, and regulate blood pressure.<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Find the lowest price for heart disease medications with BidRx.\u00a0<\/b><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"font-weight: 400;\">Heart disease, or cardiovascular disease, is the <\/span><a href=\"https:\/\/www.cdc.gov\/heartdisease\/facts.htm\"><span style=\"font-weight: 400;\">leading cause of death<\/span><\/a><span style=\"font-weight: 400;\"> for both men and women in the United States. For many people living with heart problems, beta blockers can keep their hearts pumping strong \u2014 even after a heart attack.<\/span><\/p>\n<h2>What Are Beta Blockers?<\/h2>\n<p><span style=\"font-weight: 400;\">Beta blockers are medicines commonly prescribed to treat heart and circulatory problems. These drugs help lower blood pressure by slowing and regulating heart rate and in some cases, widening veins and arteries to improve blood flow.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Beta blockers (sometimes written as \u03b2-blockers), are also called beta adrenergic blocking agents because they target the stress hormones adrenaline and noradrenaline, responsible for the \u201cfight or flight\u201d state. These hormonal signals can cause the heart to work harder than it needs to, and for people with cardiovascular problems, this extra work can harm the heart.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Beta blockers may be used to treat ongoing cardiovascular conditions or protect against future heart attacks. Because they lower the effects of stress hormones, they are sometimes used to treat anxiety or panic attacks as well.\u00a0<\/span><\/p>\n<h2>How Do Beta Blockers Work?<\/h2>\n<p><span style=\"font-weight: 400;\">Throughout the body, tiny structures called beta receptors receive information from hormones, neurotransmitters, and other chemical messengers.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532906\/\"><span style=\"font-weight: 400;\">two main types of beta receptors<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Beta-1, mostly found in the heart<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Beta-2, mainly found in the lungs and blood vessels<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These structures have specialized shapes that allow them to interact with specific signals, like adrenaline, which can increase heart rate and blood pressure.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Beta blockers work by blocking these receptors, which helps lower heart rate and reduce blood pressure.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Selective beta blockers focus on beta-1 receptors, mainly affecting the heart, while nonselective ones impact both the heart and lungs. Nonselective beta blockers can be helpful in controlling the heart rate and widening the blood vessels. Both types of beta blockers can be good treatments for heart disease because blocking the beta receptors can lessen the impact of stress hormones on the body.<\/span><\/p>\n<h2>Selective Beta Blockers<\/h2>\n<p><span style=\"font-weight: 400;\">Selective beta blockers primarily target beta-1 receptors, making them more specific to the heart than non-selective beta blockers. For this reason, selective beta blockers are sometimes called cardioselective beta blockers.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The adrenal glands release adrenaline and norepinephrine, which are a crucial part of the body\u2019s fight-or-flight response. While they\u2019re vital to survival, these hormones impact the function of the heart and blood vessels. If you have heart disease, they can put excess stress on your body. By targeting the beta-1 receptors, selective beta blockers are able to moderate the negative effect on the heart.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Selective beta blockers may be prescribed for several cardiovascular conditions including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure (hypertension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain (angina pectoris)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irregular heartbeat (arrhythmia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart failure<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These drugs can also be prescribed for off-label use at a doctor\u2019s discretion. Selective beta blockers can be used to treat:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Migraines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety and panic attacks<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Selective beta blockers usually come in pill form and are only available by prescription.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/metoprolol\"><span style=\"font-weight: 400;\">Metoprolol<\/span><\/a><span style=\"font-weight: 400;\"> (Lopressor, Toprol-XL)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/atenolol\"><span style=\"font-weight: 400;\">Atenolol<\/span><\/a><span style=\"font-weight: 400;\"> (Tenormin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/bisoprolol-fumarate\"><span style=\"font-weight: 400;\">Bisoprolol<\/span><\/a><span style=\"font-weight: 400;\"> (Zebeta, Concor)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/nebivolol\"><span style=\"font-weight: 400;\">Nebivolol<\/span><\/a><span style=\"font-weight: 400;\"> (Bystolic)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.drugs.com\/mtm\/betaxolol.html\"><span style=\"font-weight: 400;\">Betaxolol<\/span><\/a><span style=\"font-weight: 400;\"> (Kerlone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.drugs.com\/mtm\/acebutolol.html\"><span style=\"font-weight: 400;\">Acebutolol<\/span><\/a><span style=\"font-weight: 400;\"> (Sectral)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.drugs.com\/mtm\/esmolol.html\"><span style=\"font-weight: 400;\">Esmalol<\/span><\/a><span style=\"font-weight: 400;\"> (Brevibloc)<\/span><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1512\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/10\/pharmacist-getting-medicine-off-the-shelves.jpg\" alt=\"pharmacist getting medicine off the shelves\" width=\"780\" height=\"520\" \/><\/p>\n<h3>Warnings and Contraindications \u2014 Selective Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">If you are using selective beta blockers, make sure you have your medication available at all times. Refill prescriptions promptly; skipped doses could cause side effects. Don\u2019t suddenly stop taking a selective beta blocker \u2014 it could put you at risk of a heart attack or other heart problem.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Always follow your doctor\u2019s instructions, and speak with your doctor before adjusting the dosage of any medications you take. Some people are at a higher risk of death with certain beta blockers, so don\u2019t use them if you are allergic.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you have any of the following conditions, be sure your doctor knows about it before you start a selective beta blocker:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain types of arrhythmias<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow heart rate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver or thyroid problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asthma<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Tell your doctor if you are pregnant or plan to become pregnant. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5818837\/#:~:text=%CE%B2%2DBlockers%20are%20the%20most,physiological%20changes%20in%20the%20fetus.\"><span style=\"font-weight: 400;\">Beta blockers cross the placenta<\/span><\/a><span style=\"font-weight: 400;\"> and can have a cardiovascular effect on unborn babies.<\/span><\/p>\n<h3>Side Effects \u2014 Selective Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Common side effects of selective beta blockers may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cold extremities<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upset stomach<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth or eyes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia or nightmares<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headaches<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This list is not exhaustive, and it may not apply to all types of selective beta blockers. Talk to your doctor about all the side effects you experience.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Severe side effects of selective beta blockers can include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow heart rate (bradycardia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in blood sugar levels<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you experience any of these severe side effects, seek medical attention right away. If you are allergic to selective beta blockers, you may experience symptoms of anaphylaxis, like:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling face, lips, tonge, or throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Allergic reactions can be life-threatening, so if you experience any of these symptoms, seek medical attention immediately.<\/span><\/p>\n<h3>Drug Interactions \u2014 Selective Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Because selective beta blockers affect the way your body uses and reacts to certain chemical compounds, they can interact with other medications. It\u2019s important to talk to your doctor about <\/span><i><span style=\"font-weight: 400;\">all <\/span><\/i><span style=\"font-weight: 400;\">drugs and medications you\u2019re taking \u2014 including prescription drugs and all over-the-counter medications, supplements, and herbal products.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Selective beta blockers may interact with various drugs, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antiarrhythmic medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antidepressants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calcium channel blockers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anticoagulants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antihistamines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs (NSAIDs)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">No drug interaction list is complete, and not all selective beta blockers have the same interactions. Visit the Drugs.com <\/span><a href=\"https:\/\/www.drugs.com\/drug_interactions.html\"><span style=\"font-weight: 400;\">Drug Interaction Checker<\/span><\/a><span style=\"font-weight: 400;\"> to find all known interactions for your specific medication.<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1513\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/10\/man-jogging-by-the-beach.jpg\" alt=\"man jogging by the beach\" width=\"780\" height=\"519\" \/><\/p>\n<h2>Non-Selective Beta Blockers<\/h2>\n<p><span style=\"font-weight: 400;\">Unlike selective beta blockers that target the beta-1 receptors in and around the heart, non-selective beta blockers can have an effect on both beta-1 and beta-2 receptors, which are located mostly in the lungs and blood vessels.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Natural compounds like epinephrine, dopamine, and norepinephrine influence these receptors, impacting both the cardiovascular system and respiratory function. For this reason, non-selective beta blockers can provide broader treatment for heart disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some non-selective beta blockers have <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1977302\/\"><span style=\"font-weight: 400;\">intrinsic sympathomimetic activity (ISA)<\/span><\/a><span style=\"font-weight: 400;\">. This activates the beta receptors while preventing them from binding too much \u2014 think of it as a dimmer switch for the heart rate. ISA prevents the heart rate from slowing too much (bradycardia) during rest and can keep the cardiac output from getting too low.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like selective beta blockers, non-selective beta blockers may be prescribed for conditions including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypertension<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Angina pectoris<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Arrhythmias<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Migraine prevention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety and panic attacks<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This type of medication may also be used to treat glaucoma, an eye condition that puts excess pressure on the optic nerve. For this use, non-selective beta blockers are used in the form of eye drops.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Non-selective beta blockers are only available by prescription. Some common types of this medication include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/propranolol\"><span style=\"font-weight: 400;\">Propranolol<\/span><\/a><span style=\"font-weight: 400;\"> (Inderal, Innopran)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/timolol\"><span style=\"font-weight: 400;\">Timolol<\/span><\/a><span style=\"font-weight: 400;\"> (Blocadren, Timol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/carvedilol\"><span style=\"font-weight: 400;\">Carvedilol<\/span><\/a><span style=\"font-weight: 400;\"> (Coreg)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/labetalol\"><span style=\"font-weight: 400;\">Labetalol<\/span><\/a><span style=\"font-weight: 400;\"> (Normodyne, Trandate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/sotalol\"><span style=\"font-weight: 400;\">Sotalol<\/span><\/a><span style=\"font-weight: 400;\"> (Betapace, Sorine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.drugs.com\/mtm\/nadolol.html\"><span style=\"font-weight: 400;\">Nadolol<\/span><\/a><span style=\"font-weight: 400;\"> (Corgard)<\/span><\/li>\n<\/ul>\n<h3>Warnings and Contraindications \u2014 Non-Selective Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Only take non-selective beta blockers as prescribed by your doctor. Avoid skipping doses and don\u2019t suddenly stop taking your medication. Missed doses of non-selective beta blockers can result in side effects that may put you at risk of a serious heart problem.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Always speak with your doctor before adjusting the dosage of any medications you take. If you have an allergy to non-selective beta blockers or develop an allergic reaction over time, you should not take them.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Before starting any non-selective beta blocker medication, tell your doctor about any of the following conditions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain types of arrhythmias<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow heart rate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver or thyroid problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asthma or COPD<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Be sure to tell your doctor about any breathing conditions you have. Non-selective beta blockers have an effect on the beta receptors in your lungs, so some people may be at higher risk of respiratory side effects. Certain non-selective beta blockers can lead to bronchoconstriction (narrowing of the airways), so they are not recommended for people with serious respiratory conditions.<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1514\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/10\/heart-prop-in-a-doctors-office.jpg\" alt=\"heart prop in a doctor's office\" width=\"780\" height=\"516\" \/><\/p>\n<h3>Side Effects \u2014 Non-Selective Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Common side effects of selective beta blockers may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cold extremities<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upset stomach<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth or eyes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia or nightmares<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sexual side effects<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headaches<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This list is not exhaustive, and some effects may not apply to all types of non-selective beta blockers. Talk to your doctor about all the side effects you experience.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Seek medical attention right away if you experience severe side effects of non-selective beta blockers, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble breathing or an asthma attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow heart rate (bradycardia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in blood sugar levels<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Allergic reactions can be serious. Seek immediate medical attention if you experience signs of an allergic reaction, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the face, lips, tongue, or throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing<\/span><\/li>\n<\/ul>\n<h3>Drug Interactions \u2014 Non-Selective Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Like any drug, it is possible for non-selective beta blockers to interact with other prescriptions, supplements, herbs, and over-the-counter medications. Non-selective beta blockers may interact with the following drugs:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antiarrhythmic medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antidepressants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calcium channel blockers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anticoagulants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antihistamines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Monoamine oxidase inhibitors (MAOIs)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs (NSAIDs)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">No drug interaction list is complete. Visit the Drugs.com <\/span><a href=\"https:\/\/www.drugs.com\/drug_interactions.html\"><span style=\"font-weight: 400;\">Drug Interaction Checker<\/span><\/a><span style=\"font-weight: 400;\"> to find all known interactions for your specific medication.<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1515\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/10\/doctor-holding-a-stethoscope-.jpg\" alt=\"doctor holding a stethoscope\" width=\"780\" height=\"439\" \/><\/p>\n<h2>Combined Alpha and Beta Blockers<\/h2>\n<p><span style=\"font-weight: 400;\">Some non-selective beta blockers have the ability to <\/span><a href=\"https:\/\/bidrx.com\/blog\/blood-pressure-medications\/alpha-blockers\/\"><span style=\"font-weight: 400;\">block alpha receptors<\/span><\/a><span style=\"font-weight: 400;\"> as well. Alpha (\u03b1) receptors are found in many parts of the body, including the smooth muscles that control the constriction of blood vessels. When stimulated by adrenaline, alpha receptors tighten the arteries, which increases blood pressure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Combined alpha and beta blockers <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19491545\/\"><span style=\"font-weight: 400;\">relax the smooth muscles in the blood vessels<\/span><\/a><span style=\"font-weight: 400;\"> and decrease heart rate at the same time. For people with cardiovascular problems, combined alpha and beta blockers can be an effective way to manage high blood pressure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Combined alpha and beta blockers are also used to treat:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Angina pectoris<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain arrhythmias<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Renal hypertension<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Migraines<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In some cases, combined alpha and beta blockers can be used to <\/span><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(19)31282-6\/fulltext\"><span style=\"font-weight: 400;\">treat high blood pressure in pregnant women<\/span><\/a><span style=\"font-weight: 400;\">. Like other beta blockers, this drug can cross the placental barrier and affect unborn babies, but studies show that the <\/span><a href=\"https:\/\/www.drugs.com\/pregnancy\/labetalol.html\"><span style=\"font-weight: 400;\">benefits may outweigh the risks<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Combined alpha and beta blockers are only available by prescription. The most common types of combined alpha and beta blockers are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/carvedilol\"><span style=\"font-weight: 400;\">Carvedilol<\/span><\/a><span style=\"font-weight: 400;\"> (Coreg)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/labetalol\"><span style=\"font-weight: 400;\">Labetalol<\/span><\/a><span style=\"font-weight: 400;\"> (Trandate)<\/span><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1516\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/10\/measuring-blood-pressure.jpg\" alt=\"measuring blood pressure\" width=\"780\" height=\"520\" \/><\/p>\n<h3>Warnings and Contraindications \u2014 Combined Alpha and Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Always take medications as prescribed by your doctor. Avoid skipping doses and do not take an extra dose to make up for a missed one. Talk to your doctor if you have an allergy to your medications. Don\u2019t suddenly stop taking combined alpha and beta blockers because it may result in rebound hypertension (a sudden increase in blood pressure).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Before taking combined alpha and beta blockers, tell our doctor if you have any of the following conditions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain types of arrhythmias<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow heart rate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver or thyroid problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Peripheral artery disease (PAD)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asthma or COPD<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy<\/span><\/li>\n<\/ul>\n<h3>Side Effects \u2014 Combined Alpha and Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Taking combined alpha and beta blockers may result in side effects, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cold extremities<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upset stomach<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia or nightmares<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headaches<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Not everyone will experience the same side effects, and this list is not exhaustive. Depending on your needs, the benefits of combined alpha and beta blockers may outweigh the side effects. Always talk to your doctor about any side effects you experience.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Severe side effects can include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow heart rate (bradycardia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in blood sugar levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wheezing or shortness of breath<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Signs of a serious allergic reaction include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the face, lips, tongue, or throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Seek immediate medical attention if you experience an allergic reaction or other severe side effects.<\/span><\/p>\n<h3>Drug Interactions \u2014 Combined Alpha and Beta Blockers<\/h3>\n<p><span style=\"font-weight: 400;\">Be sure to talk to your doctor about all prescriptions, over-the-counter medications, supplements, and herbal products you\u2019re taking. Combined alpha and beta blockers are <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK534787\/\"><span style=\"font-weight: 400;\">usually well tolerated<\/span><\/a><span style=\"font-weight: 400;\">, but they may interact with certain drugs including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antihypertensive medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calcium channel blockers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insulin and antidiabetic agents<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Monoamine oxidase inhibitors (MAOIs)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs (NSAIDs)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Not all combined alpha and beta blockers have the same interactions, and no drug interaction list is complete. Visit the Drugs.com <\/span><a href=\"https:\/\/www.drugs.com\/drug_interactions.html\"><span style=\"font-weight: 400;\">Drug Interaction Checker<\/span><\/a><span style=\"font-weight: 400;\"> to find all known interactions for your specific medication.<\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1517\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/10\/keeping-a-healthy-heart.jpg\" alt=\"keeping a healthy heart\" width=\"780\" height=\"520\" \/><\/p>\n<h2>Beta Blockers Can Be Life-Saving Medications<\/h2>\n<p><span style=\"font-weight: 400;\">Beta blockers are some of the <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/22318-beta-blockers#:~:text=Beta%2Dblockers%20are%20some%20of,adults%20using%20a%20beta%2Dblocker.\"><span style=\"font-weight: 400;\">most commonly prescribed<\/span><\/a><span style=\"font-weight: 400;\"> medications in the United States, and an estimated 30 million adults rely on these medications to support heart health. Selective, non-selective, and combined alpha and beta blockers all work to reduce the effects of stress on the heart and keep blood pressure under control. For people who have experienced a heart attack, beta blockers may be the key for keeping the heart strong and steady.\u00a0<\/span><\/p>\n<h2>Find the Lowest Price for Heart Disease Medications<\/h2>\n<p><span style=\"font-weight: 400;\">If your doctor has prescribed beta blockers, you can get your heart disease medications at an affordable price with BidRx. Use BidRx to compare prices from pharmacies across the country, then have your prescriptions delivered or available for local pickup. To get started, <\/span><a href=\"https:\/\/www.bidrx.com\/home\/ailment_details\/?ailment=High%20Blood%20Pressure&amp;__mscta=3160_98751_15220\"><span style=\"font-weight: 400;\">see all blood pressure medications<\/span><\/a><span style=\"font-weight: 400;\"> and create your bid to find the lowest price for your heart disease medications today.<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">This information is intended for general informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication.\u00a0<\/span><\/i><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this guide to beta blockers, learn how chemical signals impact heart health and where you can find the lowest price for heart disease medications.<\/p>\n","protected":false},"author":2,"featured_media":1511,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7,50],"tags":[],"class_list":["post-1341","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blood-pressure-medications","category-cholesterol-medications","category-heart-failure-medications"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1341","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/comments?post=1341"}],"version-history":[{"count":7,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1341\/revisions"}],"predecessor-version":[{"id":1518,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1341\/revisions\/1518"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media\/1511"}],"wp:attachment":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media?parent=1341"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/categories?post=1341"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/tags?post=1341"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}