{"id":1023,"date":"2023-06-08T09:00:12","date_gmt":"2023-06-08T09:00:12","guid":{"rendered":"https:\/\/www.bidrx.com\/blog\/?p=1023"},"modified":"2023-09-08T14:59:21","modified_gmt":"2023-09-08T14:59:21","slug":"lisinopril","status":"publish","type":"post","link":"https:\/\/www.bidrx.com\/blog\/diabetes-medications\/lisinopril\/","title":{"rendered":"About Lisinopril: A Patient&#8217;s Guide"},"content":{"rendered":"<p><b>Highlights<\/b><b><\/b><\/p>\n<ul>\n<li aria-level=\"1\"><b>Lisinopril is primarily used to treat high blood pressure and can also be used to treat kidney problems in people with diabetes.<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>An angiotensin-converting enzyme (ACE) inhibitor, lisinopril acts on a key hormone cycle for regulating blood pressure.<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>If you have kidney or liver disease, you may need to seek other blood pressure treatment options.<\/b><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"font-weight: 400;\">Hypertension, also called high blood pressure, is a major contributor to complications and deaths surrounding a wide range of medical issues, most notably heart disease. If you have high blood pressure, your doctor might prescribe lisinopril. Learn what lisinopril is used for, how it works, who should and shouldn\u2019t take it, and how to get the lowest price for lisinopril.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What Is Lisinopril and What Is It Used For?<\/span><\/h2>\n<p><a href=\"https:\/\/www.bidrx.com\/home\/Medicine_Details\/lisinopril-20-mg-tablet\"><span style=\"font-weight: 400;\">Lisinopril<\/span><\/a><span style=\"font-weight: 400;\"> is a first-line treatment for high blood pressure. Lisinopril is also used for symptoms related to heart attacks and heart failure and to manage blood pressure immediately after a heart attack. If you have kidney problems related to diabetes, you may also be prescribed lisinopril.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lisinopril is sold under many brand names, including Zestril, Prinivil, and Qbrelis. The generic version became available in 1987.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How Does Lisinopril Work?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lisinopril is an <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482230\/\"><span style=\"font-weight: 400;\">angiotensin-converting enzyme (ACE) inhibitor<\/span><\/a><span style=\"font-weight: 400;\">. ACE inhibitors help manage blood pressure by specifically targeting and inhibiting the enzyme ACE. By blocking ACE, lisinopril prevents the conversion of angiotensin I into angiotensin II. Angiotensin II is a potent vasoconstrictor, meaning it narrows the blood vessels and increases blood pressure.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">By reducing the levels of angiotensin II, lisinopril helps to relax and widen the blood vessels, allowing for improved blood flow. This action helps to maintain healthy blood pressure levels and reduce the strain on the heart and cardiovascular system.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Lisinopril Dosage and Administration<\/span><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1025\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/06\/2.jpeg-2-1.jpg\" alt=\"putting pills in dispenser\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Lisinopril is taken orally, either as a capsule or in solution form. Generally, adults will start with 10 milligrams once daily, moving towards a maintenance dose of 20 milligrams and can receive doses as high as 40 milligrams.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lisinopril can be stored anywhere away from moisture and heat, and solutions should not be frozen.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lisinopril can be taken with or without food and should be paired with a hydration regimen to limit side effects and other problems.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What Formulas Are Available for Lisinopril?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lisinopril is most often prescribed as a stand-alone drug, but it is also available in combination with other medications. The most common combinations include:<\/span><\/p>\n<p><b>Lisinopril-hydrochlorothiazide:<\/b><span style=\"font-weight: 400;\"> This combination medication includes <\/span><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/lisinopril-hctz-10-12.5-tab\"><span style=\"font-weight: 400;\">lisinopril and hydrochlorothiazide<\/span><\/a><span style=\"font-weight: 400;\">, which is a diuretic (water pill). It is commonly prescribed to treat high blood pressure by reducing fluid retention and lowering blood pressure.<\/span><\/p>\n<p><b>Lisinopril-amlodipine:<\/b><span style=\"font-weight: 400;\"> This combination medication combines lisinopril with amlodipine, which is a calcium channel blocker. It is used to treat high blood pressure by relaxing the blood vessels and improving blood flow.<\/span><\/p>\n<p><b>Lisinopril-hydrochlorothiazide-amlodipine: <\/b><span style=\"font-weight: 400;\">This combination medicine contains lisinopril, hydrochlorothiazide, and amlodipine. It is prescribed for the treatment of high blood pressure when multiple medications are needed to control blood pressure levels effectively.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">HCTZ prevents the kidneys from retaining water, helping to flush more sodium out of the body. Reducing fluid volume can help drive down blood pressure, although it\u2019s important to maintain a balance.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What Are the Potential Side Effects of Lisinopril?<\/span><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1026\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/06\/3.jpeg-2-1.jpg\" alt=\"woman drinking water\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">The most common side effect of lisinopril is dehydration. Because it interferes with one of the ways the body manages fluids, dehydration is more of a risk when you\u2019re taking lisinopril. Talk to your doctor about a hydration regimen and what to avoid while taking it, as some common drinks like coffee and alcohol may potentially have diuretic effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Review what to do if you\u2019re experiencing a medical condition that causes dehydration, such as diarrhea, ongoing vomiting, or excess sweating. These can speed up dehydration and can catch patients by surprise if they\u2019re not monitoring their fluid intake. If you live in a warm area, lisinopril can increase your risk of heatstroke.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other possible common side effects of lisinopril include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">There is the potential for more serious side effects, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acute kidney injury due to elevated creatinine or blood urea nitrogen (BUN) levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated blood potassium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling under the skin (angioedema)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe cough<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Who Shouldn\u2019t Take Lisinopril?<\/span><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-1027\" src=\"https:\/\/www.bidrx.com\/blog\/wp-content\/uploads\/2023\/06\/4.jpeg-2.jpg\" alt=\"doctor giving a prescription\" width=\"780\" height=\"520\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Before taking lisinopril, review your medical history with your doctor, particularly if you\u2019ve ever had:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any form of kidney disease\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any type of liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of angioedema (swelling just under the skin or mucous membranes anywhere on the body.)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood potassium levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Are currently on dialysis or may need to begin dialysis in the near future<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you\u2019ve never taken an ACE inhibitor before, request an allergy test to ensure it\u2019s safe to take, and let your doctor know if you\u2019ve ever had an allergic reaction to an ACE inhibitor, even a minor one. If you\u2019re pregnant or may become pregnant, <\/span><b>do not take lisinopril<\/b><span style=\"font-weight: 400;\">, as it may harm the baby.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Are There any Potential Drug Interactions with Lisinopril?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lisinopril has several drug interactions you need to be aware of. Be sure that all your providers are aware of all drugs and supplements that you take.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The drugs that can have potentially dangerous interactions with lisinopril include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Sacubitril (<\/b><a href=\"https:\/\/www.bidrx.com\/home\/medicine_details\/entresto-24-mg-26-mg-tablet\"><b>Entresto<\/b><\/a><b>).<\/b><span style=\"font-weight: 400;\"> Another type of antihypertensive. Don\u2019t take lisinopril within 36 hours of a dose of sacubitril.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.drugs.com\/mtm\/aliskiren.html\"><b>Aliskiren<\/b><\/a><b> (Tekturna, Rasilez).<\/b><span style=\"font-weight: 400;\"> If you have diabetes, do not take lisinopril together with any medication that contains aliskiren.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Erectile dysfunction drugs such as <\/b><a href=\"https:\/\/www.drugs.com\/sildenafil.html\"><b>sildenafil<\/b><\/a><b>. <\/b><span style=\"font-weight: 400;\">ED drugs are generally vasodilators and may not be recommended, depending on how you control your blood pressure.\u00a0<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Nonsteroidal anti-inflammatory drugs (NSAIDS). <\/b><span style=\"font-weight: 400;\">NSAIDs (pain relievers like Tylenol, ibuprofen, and aspirin) can weaken the effectiveness of lisinopril in lowering blood pressure and may <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2218652\/\"><span style=\"font-weight: 400;\">increase the risk of kidney problems<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Certain diabetes medications<\/b><span style=\"font-weight: 400;\">. Lisinopril can sometimes enhance the blood sugar-lowering effects of oral hypoglycemic agents or insulin, leading to a potential risk of low blood sugar levels (hypoglycemia). If your doctor prescribes lisinopril while you\u2019re taking one of these diabetes medications, your doctor will want to closely monitor your blood sugar levels and adjust the dosage of diabetes medications as needed.\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Potassium supplements. <\/b><span style=\"font-weight: 400;\">Lisinopril can increase the levels of potassium in the body. Taking additional potassium supplements can further elevate potassium levels to potentially dangerous levels.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">What Other Precautions Should I Take With Lisinopril?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As with all medications, there are precautions that you should take if you\u2019re taking lisinopril. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Follow the prescribed dosage: <\/b><span style=\"font-weight: 400;\">It is important to take lisinopril exactly as prescribed by a healthcare professional. Do not take more or less than the prescribed dose without consulting a doctor.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Stay hydrated: <\/b><span style=\"font-weight: 400;\">Lisinopril can sometimes cause excessive fluid loss due to its effects on blood pressure and fluid balance. Ensure you drink an adequate amount of water and stay hydrated while taking the medication.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Keep your healthcare providers informed: <\/b><span style=\"font-weight: 400;\">Before starting lisinopril, inform your provider about any existing medical conditions, including allergies, kidney disease, liver disease, heart conditions, diabetes, or if you are pregnant or breastfeeding.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Monitor blood pressure and kidney function: <\/b><span style=\"font-weight: 400;\">Regularly monitor your blood pressure while taking lisinopril and keep track of any changes. Additionally, your doctor may order periodic blood tests to evaluate kidney function, as lisinopril can affect kidney function in some individuals.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Avoid pregnancy:<\/b><span style=\"font-weight: 400;\"> Lisinopril is not recommended during pregnancy, as it can cause harm to the developing fetus. If you become pregnant while taking lisinopril, inform your doctor immediately.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Report side effects: <\/b><span style=\"font-weight: 400;\">If you experience any unusual side effects while taking lisinopril, such as dizziness, persistent cough, swelling, or difficulty breathing, contact your prescribing provider promptly.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Get the Lowest Price for Lisinopril with BidRx<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Managing your blood pressure isn\u2019t just about medication, but also about limiting stress. BidRx helps you focus on your health, not your budget by giving you the tools to put your <\/span><a href=\"https:\/\/www.bidrx.com\/home\/Medicine_Details\/lisinopril-20-mg-tablet\"><span style=\"font-weight: 400;\">lisinopril<\/span><\/a><span style=\"font-weight: 400;\"> prescription up for bid by pharmacies around the country. Choose the bid that works for you, and it\u2019ll be shipped straight to your door, or you can pick it up locally, depending on the offer you choose.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Get started on <\/span><a href=\"https:\/\/www.bidrx.com\/home\/Contents\/medication\"><span style=\"font-weight: 400;\">our medications page<\/span><\/a><span style=\"font-weight: 400;\"> and learn how much you can save!<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Highlights Lisinopril is primarily used to treat high blood pressure and can also be used&hellip;<\/p>\n","protected":false},"author":2,"featured_media":1306,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45,18,50],"tags":[],"class_list":["post-1023","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-chronic-kidney-disease-medications","category-diabetes-medications","category-heart-failure-medications"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1023","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/comments?post=1023"}],"version-history":[{"count":5,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1023\/revisions"}],"predecessor-version":[{"id":1035,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/posts\/1023\/revisions\/1035"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media\/1306"}],"wp:attachment":[{"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/media?parent=1023"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/categories?post=1023"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bidrx.com\/blog\/wp-json\/wp\/v2\/tags?post=1023"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}